Postdoctoral Researcher 2010 – UK
Postdoctoral Researcher At Modelling The Spatiotemporal Dynamics Of Viral Docking At UK In 2010
Description:
The Department of Computational and Systems Biology conducts theoretical and applied research across a broad range of the biological sciences, with a special focus on plant and microbial research. Particular strengths of the department include comparative genomics, mathematical and statistical modelling, semantic modelling and data integration, biological physics and structural biology. In addition, our user support role underpins the research of the institute through training, software development and statistical analysis.Much of the research is carried out in collaboration with world-leading experimental groups within the John Innes Centre whilst also maintaining strong collaborations with experimentalists and theoreticians within the Norwich Research Park, across the UK and Internationally.Group Details:
The Howard group mathematically models biological systems at a variety of scales ranging from subcellular up to the level of embryonic development. A key interest is in uncovering complex dynamics even in systems with few components and apparently simple interactions. Such dynamics occur frequently in biological systems, especially those exhibiting pattern forming and/or stochastic behaviour. The group’s approach is highly interdisciplinary, and relies heavily on techniques from statistical physics as well as on close collaboration with experimental groups both at the John Innes Centre and elsewhere. Currently there are two Postdoctoral Researchers and one Masters student in the group.
Aims Of Job:
The aim of the project is to mathematically model the dynamics of viral infection of the bacterium Caulobacter crescentus. This will involve dissecting the spatiotemporal dynamics of viral entry, the role of the bacterial cytoskeleton, and the impact of the virus on cell cycle dynamics. The modelling will involve a combination of ordinary/partial differential equations and Monte-Carlo simulations. The investigation will be carried out in close collaboration with the Wright group (Atlanta, electron cryo-tomography) and the Viollier group (Geneva, fluorescence microscopy and genetics). Experimental results from the Viollier/Wright labs will be used to test ideas from the theory, and thereby iteratively improve the model.
Person Specification:
The postholder will be an outstanding scientist who has, or expects soon to receive, a PhD in Theoretical Physics, Biomathematics or related subject. We are looking for a self-motivated and creative individual, who can contribute with new ideas. Prior experience in modelling biological systems is not essential, but we expect the postholder to enthusiastically seek new challenges in quantitative biology. The successful candidate must be available to travel to international meetings and for short visits to the two collaborating laboratories abroad. We will be providing the postholder with opportunities to develop their technical and transferable skills during this assignment, by way of training programmes, coaching and mentoring.
Duties & Responsibilities:
Performing scientific research, writing papers and attending scientific meetings
Address:
John Innes Centre
Norwich Research Park
Colney
Norwich
NR4 7UH
UK
Telephone No: +44 (0)1603 450000
Fax: +44 (0)1603 450045
Last Date To Apply:26 November 2010
Source:http://jobs.jic.ac.uk/Details.asp?vacancyID=2728
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